Jun 6, 2023 10:50:43 AM | Ai Unleashing the Secrets of FFPE Samples & Transforming Research with AI

Unleashing the Hidden Secrets of Cancer: A Breakthrough in Nucleic Acid Extraction from FFPE Samples, What This Means For Research, and How AI Can Help

The Strength of Synergy: TCAP AI and Nucleic Acid Extraction from FFPE Samples

In the ever-evolving landscape of precision medicine, groundbreaking advancements continue to reshape the field, empowering researchers, clinicians, and pathologists alike. These advancements include improved methods for the extraction of nucleic acids from formalin-fixed paraffin-embedded (FFPE) samples and the utilization of TriMetis' Computer-Assisted Pathology (TCAP) AI in analyzing digital H&E images from FFPE samples. These innovations share a common goal: to unlock genetic information and improve diagnostic accuracy.

Traditionally, extracting nucleic acids from FFPE samples posed significant challenges due to degradation and chemical modifications. However, a paradigm-shifting breakthrough in extraction protocols now enables the recovery of high-quality DNA and RNA. This revolutionizes molecular diagnostics by uncovering critical genetic insights, allowing for personalized treatment decisions, prognostic assessments, and therapeutic interventions. By harnessing the power of FFPE samples, researchers and clinicians gain access to a wealth of genetic information, propelling precision medicine to new heights.

Similarly, having been trained by Board Certified Pathologists TCAP leverages AI and machine learning to revolutionize pathology. By integrating advanced algorithms, TCAP automates time-consuming tasks and streamlines the analysis of digital H&E images from FFPE samples. Pathologists can now delegate mundane activities, such as counting nuclei, to AI applications, enabling them to focus on supporting patient care and making informed treatment decisions. TCAP enhances efficiency, reduces turnaround times, and provides valuable insights into which cases require further testing or review. By uncovering subtle patterns, identifying rare or challenging cases, and expanding diagnostic skills, TCAP transforms the field of pathology.

Jon Wetzel, COO of TriMetis, said, "As a Lean Six Sigma guy I love that TCAP AI is removing jobs from the pathologists that they don't enjoy while also giving them tools to make their daily work more straightforward and efficient, it's a win for the process and the pathologist at the same time."

As we pave the way for a future where precision medicine thrives, the combination of the advancements made in methods for nucleic acid extraction from FFPE samples stands as a testament to innovation. These advancements empower researchers, clinicians, and pathologists with unparalleled capabilities and insights, revolutionizing the way we diagnose, treat, and understand diseases. From unlocking the genetic secrets hidden in FFPE samples to harnessing the power of AI in pathology, we welcome a new era of healthcare, where precision medicine reaches new heights and patient care is transformed. These game-changers redefine the boundaries of what is possible, shaping a future where precision medicine becomes the standard of care. Welcome to the new path forward, where the fusion of science, technology, and human expertise revolutionizes patient outcomes.

To read the National Cancer Institute's publication on DNA and RNA Extraction From Formalin-Fixed, Paraffin-Embedded Tissue Biospecimens in full head to Biospecimens.Cancer.gov.

Written By: Kaitlynn Clement